The non-coding genome, once dismissed as "junk DNA", is now recognized as a fundamental regulator of gene expression and a key player in understanding complex diseases. Following the landmark ...

The human genome contains about 20,000 protein-coding genes, but that only accounts for roughly two percent of the genome. For many years, it was easier for scientists to simply ignore all of that ...

"With up to half of individuals with rare diseases currently living without a diagnosis, exploring the non-coding DNA can provide answers for families with rare conditions." The researchers found that ...

Researchers have revealed that so-called ‘junk DNA’ contains powerful switches that help control brain cells linked to Alzheimer’s disease. When people picture DNA, they often imagine a set of genes ...

Researchers have identified a portion of the human genome known as PTCHD1-AS on the X chromosome that does not code for ...

Almost 1,500 genes have been implicated in intellectual disabilities; yet for most people with such disabilities, genetic causes remain unknown. Perhaps this is in part because geneticists have been ...

Scientists have found new genetic causes for diabetes in babies – in a part of the genome that has historically been overlooked in genetic studies. Until recently, most research has investigated ...

Researchers have pinpointed a long non-coding gene that plays a distinct role in the social and stereotypic repetitive ...

A new study identifies PTCHD1-AS as a key non-coding gene that shapes social and repetitive behaviors in autism without affecting cognition.