Bioactive sphingolipids constitute a family of lipids, including sphingosine, ceramide, sphingosine-1-phosphate (S1P) and ceramide-1-phosphate. These molecules act on distinct protein targets, ...

Please provide your email address to receive an email when new articles are posted on . Previous research has linked sphingolipids with asthma. Patients with asthma had lower levels of sphingolipids ...

Glyn Dawson, an expert on lipid biochemistry and longtime professor in the Departments of Pediatrics and Biochemistry and ...

Plasma ceramides and sphingomyelins with palmitic acid were linked to a 34% and 37% increased risk of sudden cardiac death (SCD) per higher SD of log sphingolipid levels, respectively. After looking ...

Hypercaloric diets lead to the dysregulation of multiple lipid metabolic pathways, which contributes to the onset and progression of metabolic disease Lipidomic studies are starting to decipher the ...

Excess cholesterol is known to form artery-clogging plaques that can lead to stroke, arterial disease, heart attack, and more, making it the focus of many heart health campaigns. Fortunately, this ...

Asthma is currently defined by reversible airflow obstruction, airway hyperreactivity, and airway inflammation. Of the three diagnostic criteria, asthma symptoms track most closely with airway ...

No other changes in sphingolipids were seen in the white patients, but the African American patients had increases in a number of other sphingolipids as well. Sphingosine 1-phospahte (S1P) has been ...

Investigators have uncovered a way to unleash in blood vessels the protective effects of a type of fat-related molecule known as a sphingolipid, suggesting a promising new strategy for the treatment ...

Sphingolipids are gaining strategic importance because they sit at the intersection of therapeutics, delivery science, and beauty biomimetics. In pharmaceuticals, their relevance is rising as research ...