Toll-like receptor 4 (TLR4) is a pattern recognition receptor central to innate immunity. It recognises lipopolysaccharide (LPS), an outer-membrane component of Gram-negative bacteria, via a ...
A study published in Nature by researchers at Duke University School of Medicine identifies a new way that G protein–coupled ...
Researchers have found a new receptor for nerve growth factor that plays an important role in pain signaling, even though it does not signal on its own, according to a new study. The findings hold ...
Purinergic signaling, mediated by extracellular nucleotides such as ATP and UTP, has been increasingly studied for its role in regulating cellular communication. A new review by researchers in ...
Previous research separately linked a viral protein called glycoprotein 120 (gp120) to increased pain sensitivity and ...
Researchers at the Institute of Transformative Bio-Molecules (WPI-ITbM), Nagoya University, together with collaborators from RIKEN Center for Sustainable Resource Science (RIKEN CSRS) and The ...
Over half of the people carrying HIV experience chronic pain at some point, which is difficult to treat. In a new JNeurosci ...
G protein-coupled receptors, or GPCRs, sit in the plasma membrane, the boundary that defines the inside and outside of a ...
Researchers discovered that disrupted PTH1R signaling drives abnormal cementum growth and tooth-bone fusion in adult ...
When activated in ovarian cancer cells, the receptor for the body's primary stress hormone alters the tumor environment in ...
A fruit fly is starving, and there is sugar right in front of it. Normally, that would be the end of the story. But if the ...