The new open-source atlas, generated by an AI tool called ESMFold2, vastly increases the known protein universe ...

Slime mould Dictyostelium discoideum protein complex Q55DI5 (AF-0000000066503175), annotated as a transcription elongation factor. The single chain looked disordered, but modelling the homodimer ...

Recently, SandboxAQ launched what it claims is the largest publicly available dataset of protein-ligand pairs with annotated experimental binding potency data. According to the company, the ...

Northwestern Medicine scientists have developed a new experimental method to analyze conformational fluctuations in protein ...

Targeted protein degradation (TPD) therapeutics seek to harness this intrinsic quality control machinery to selectively ...

Scientists thought they had a working map of the human proteome. Some stretches of DNA made useful proteins, while a murkier, “dark” region seemed mostly inactive or irrelevant. Turns out their map ...

Scientists have created a mega-database revealing how half a million different DNA mutations generate errors in proteins in humans. The researchers hope that the database will be used to develop new, ...