You have probably heard of dopamine. The substance also known as the "feel-good hormone". Drugs such as cocaine cause a surge of dopamine in the brain. Normally, a protein in the brain called the ...

Scientists have determined structures of a transporter protein involved in the movement of neurochemicals such as serotonin and dopamine, unearthing multiple mechanisms that can guide drug development ...

Scientists at St. Jude Children’s Research Hospital have drawn on structural biology expertise to determine structures of vesicular monoamine transporter 2 (VMAT2), a key component of neuronal ...

Neurotransmitter transporters are integral membrane proteins responsible for the rapid clearance of signalling molecules from the synaptic cleft and their return to presynaptic terminals.

Neurons talk to each other using chemical signals called neurotransmitters. Scientists at St. Jude Children's Research Hospital have drawn on structural biology expertise to determine structures of ...

A new study is shedding light on our understanding of the molecular origins of some forms of autism and intellectual disability. Researchers were able to successfully capture atomic resolution images ...

Dopamine seems to be having a moment in the zeitgeist. You may have read about it in the news, seen viral social media posts about “dopamine hacking” or listened to podcasts about how to harness what ...

This transport is slow, but allows glutamate to be transported against its concentration gradient and thus to generate high concentrations in the synaptic vesicle. Aspartate and other large anions are ...

Amphetamine is a psychostimulant that has been used to treat a variety of brain dysfunctions. However, it is a highly abused drug. In fact, amphetamine and amphetamine-derived compounds such as ...

(Memphis, Tenn – November 1, 2023) Neurons talk to each other using chemical signals called neurotransmitters. Scientists at St. Jude Children’s Research Hospital have drawn on structural biology ...