Metabolic reprogramming in tumor immunology refers to alterations in nutrient uptake and intracellular pathways that enable both cancer cells and immune cells to survive, proliferate and exert ...

Chronic lung diseases, such as COPD, pulmonary fibrosis and BPD, impose heavy global health burdens with high morbidity and mortality. Recent studies have ...

Pilatus Biosciences to Present Preclinical Data Highlighting Novel Metabolic Checkpoint Therapy PLT012 at EASL Congress 2026 ...

Solid tumors often provide a challenging environment for the T cells of our immune system. By reprogramming the metabolism of T cells, scientists at the VIB-KU Leuven Center for Cancer Biology and ...

Head and neck cancer remains a major global health challenge, ranking among the six most common cancers worldwide and claiming hundreds of thousands of lives each year. A growing body of evidence now ...

Aerobic glycolysis dominates lesion bioenergetics, with lactate promoting histone lactylation, M2 macrophage polarization, ...

Aging is a complex process that has long puzzled scientists. A recent study published in Engineering proposes a new theory called pro-aging metabolic reprogramming (PAMRP), which could change our ...

Aging is a complex process that has long puzzled scientists. A recent study published in Engineering proposes a new theory called Pro-Aging Metabolic Reprogramming (PAMRP), which could change our ...

Why do some of the most advanced cancer therapies fail against solid tumors? Despite remarkable success in blood cancers, CAR-T cell treatment is much less effective against solid tumors due to the ...

Leuven, 11 March 2025 – Solid tumors often provide a challenging environment for the T cells of our immune system. By reprogramming the metabolism of T cells, scientists at the VIB-KU Leuven Center ...

Poster presentation to showcase PLT012 targeting CD36 in metabolic dysfunction-associated steatohepatitis (MASH) Data demonstrate broad immune-metabolic reprogramming and reduction in key ...