T lymphocytes differentiate from naïve precursors upon antigen encounter into distinct effector and memory subsets. Following priming by antigen-presenting cells in lymphoid tissues, naïve CD4+ and ...
Investigators led by Navdeep Chandel, Ph.D., the David W. Cugell, MD, Professor of Medicine in the Division of Pulmonary and Critical Care, have discovered how the metabolism of mitochondria supports ...
We owe a lot to tissue resident memory T cells (T RM). These specialized immune cells are among the body's first responders to disease. Rather than coursing through the bloodstream-as many T cells ...
A preclinical mouse study in Immunity suggests that aged circulating CD8+ T cells can disrupt hippocampal function and impair ...
CD8 + cytotoxic T lymphocytes (CTLs) serve as central effectors in cancer immunotherapy by directly eliminating tumor cells. However, current clinical therapies face significant limitations. These ...
Some results have been hidden because they may be inaccessible to you
Show inaccessible results