Drug delivery systems can alter drug clearance from the peritoneal cavity and drug toxicity profiles. For example, IP injection of cisplatin-loaded polymeric microspheres (100–200 µm, which releases ...
Hyperthermic intraperitoneal chemotherapy (HIPEC) provides an important treatment option that can improve survival for some patients with advanced peritoneal cancer. Managing this disease — and ...
Please provide your email address to receive an email when new articles are posted on . Retroperitoneal exploration at the time of primary debulking surgery appeared to improve survival in patients ...
Please provide your email address to receive an email when new articles are posted on . The addition of intraperitoneal paclitaxel to systemic capecitabine and oxaliplatin appeared to benefit patients ...
EUDARIO/ENGOTov-48: A European multicenter randomised phase II trial on the combination of the HSP90 inhibitor ganetespib with carboplatin followed by maintenance treatment with niraparib (+/- ...
Another major limitation of IP therapy is the lack of efficacy in larger, bulky tumors. In ovarian cancer, the postsurgical residual tumor size is the most significant prognostic indicator for IP ...
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