If the engines of DNA replication stay in high gear all the time, they eventually stall or even break down. Fortunately, these engines, which consist of protein complexes, have what could be called ...

DNA–protein cross-links (DPCs) represent a severe form of DNA damage that can disrupt essential chromatin-based processes. Among them, DNA–histone cross-links (DHCs) occur frequently within ...

DNA nanostructures assembled in ionic liquids instead of magnesium become stable in biological conditions and bind cancer-cell markers with higher precision. (Nanowerk News) DNA nanostructures are ...

New research reveals how the RapA enzyme protects against R-loop cytotoxicity in E. coli. Genetically speaking, it's a bacterium's worst-case scenario: during transcription, newly minted RNA sticks to ...

A new study led by researchers at the University of Pittsburgh (Pitt) and UPMC Hillman Cancer Center has shown that an enzyme called PARP1 is involved in the repair of telomeres, the lengths of DNA ...

Researchers have developed a method to evaluate the folding stability of a million proteins simultaneously. DNA libraries were used to generate protein -- DNA complexes that were treated with enzymes ...

While the central dogma of molecular biology outlines the linear flow of genetic information from DNA to RNA to proteins (black lines), glycomics introduces a “3rd code of life”—glycans—that operates ...

Recent advancements in glycobiology have challenged the traditional understanding of molecular interactions, and a new study published in Engineering titled "Can DNA be glycosylated?" by Wei Wang ...

Urine sampling is a simple, non-invasive way to assess various human health parameters. As a waste product of metabolism, urine carries a wide range of molecular signatures that enable tracking of ...