The basement membrane is a specialised form of extracellular matrix that underlies epithelial and endothelial cell layers, forming a thin yet robust scaffold composed primarily of laminins, type IV ...

Focal adhesions are protein assemblies that allow cells to adhere to and interact with their surrounding matrix. DNA repair pathways and other responses to genotoxic stress have been well described, ...

Estrogen loss in aging females causes the collapse of the brain's extracellular matrix, increasing Alzheimer's risk.

A largely overlooked space between cells in women's brains may hold the key to understanding memory loss tied to estrogen ...