Cell signalling pathways are central to maintaining cellular homeostasis and regulating essential functions such as proliferation, apoptosis, and repair. In both cancer and neurodegenerative diseases, ...

Autophagy is essentially the 'rubbish collection' of our cells. If there are problems in this process, which is so important for our health, diseases such as Parkinson's can result. In their latest ...

One finding of the study, now published in the Journal of Biological Chemistry, surprised the researchers: The mice were simultaneously protected against hypertension by activating a different ...

Microtubules, part of heart muscle cells' internal "skeleton," help determine how the heart changes shape under stress, and a ...

An international study led by a scientist at the University of Ottawa Faculty of Medicine is opening new frontiers in the ...

Sepsis is a complex clinical syndrome characterized by dysregulated immune responses, systemic inflammation, and multi-organ dysfunction. It involves intricate interactions among multiple signaling ...

Within the past decade, biologists have discovered that one strategy cells use to keep their contents organized is a phenomenon known as phase separation. Similar to the way oil forms droplets that ...

The distinct aging rates of neural progenitor cells and Wnt signaling dictate mammalian cortical layer proportions.

Summary: A developmental neurobiology breakthrough uncovered a previously unmapped molecular pathway that regulates brain ...