Growing momentum for RAS inhibition at ASCO highlights Namodenoson’s RAS pathway inhibition and encouraging data in pancreatic cancerRamat Gan, ...

Cellular phase separation may play a previously underappreciated role in regulating kinase activity, offering therapeutic ...

For most children diagnosed with medulloblastoma, the most common malignant pediatric brain tumor, survival rates are ...

An AI-assisted drug discovery platform using transfer learning has identified a promising gp130 inhibitor for colorectal ...

Our body receives and processes a vast number of signals. Chemical signals serve as guidance cues and ensure, for example, ...

A previous trial involving patients with metastatic prostate cancer that was resistant to androgen pathway modulation (formerly referred to as castration-resistant) showed that adding talazoparib ...

Purinergic signaling, mediated by extracellular nucleotides such as ATP and UTP, has been increasingly studied for its role in regulating cellular communication. A new review by researchers in ...

A new review brings attention to the STING pathway as a critical regulator in both colitis and colon cancer, highlighting its complex and often opposing roles in inflammation and tumor development.

Recently, the research group led by Dr. Dechao Feng, Lecturer at University College London (UCL) and Distinguished Research ...

Signal transduction The cellular process that converts a signal, such as a hormone, growth factor, neurotransmitter, cytokine, mechanical force, or environmental cue, into biochemical changes inside ...