Two KRAS-targeted strategies are starting to reshape treatment for metastatic pancreatic cancer after decades of limited progress with chemotherapy.

Cancer researchers have spent decades cataloging mutations found in tumors, building databases that now hold millions of ...

Researchers analyzing nearly 500 feline tumors across five countries identified genetic mutations linked to cancers in humans ...

A melanoma cell can dodge a targeted drug in dozens of different ways, each driven by a different genetic mutation. But what ...

Scientists say factors that shape the microbiome early in life — including diet, antibiotics, and breastfeeding — may influence cancer risk years later.

Emphasis is placed on assembling multidisciplinary expertise, including genetic counseling and second opinions, to facilitate informed, preference-concordant management decisions. Risk-management ...

In clinical trials, the drug was shown to almost double the survival time for pancreatic cancer patients. Here's how it works ...

Chemotherapy drugs that target a common mutation in colorectal cancer rapidly lose efficacy in patients, leading to relapse.

Sperm from a single donor in Europe has reportedly been used to conceive at least 67 pregnancies, although the donor carried a rare cancer-causing mutation. The donor’s mutation has been linked to ...

When it comes to cancer, tumor suppressor genes are usually thought of as the "good guys." These genes make proteins that ...

Dr. Marwan G. Fakih explains that KRAS mutations, found in 45% of patients with colorectal cancer, include the rare KRAS G12C mutation, leading to Lumakras approval. According to the National Cancer ...

A single sperm donor who carries a rare cancer-causing genetic mutation has fathered at least 197 children across 14 countries in Europe, according to a collaborative investigation by 14 European news ...