CHICAGO -- Intracerebroventricular (ICV) delivery of bivalent CAR T-cells targeting EGFR and IL13Rα2 was feasible and appeared safe in patients with recurrent glioblastoma (GBM) in a phase I study ...
Leptomeningeal metastases (LM) occur when cancerous cells metastasize or spread to the leptomeninges, cerebral spinal fluid (CSF), or both. The meninges are thin layers of tissue surrounding and ...
The human central nervous system is bathed in cerebrospinal fluid (CSF), which is produced by the choroid plexus, circulates through ventricular and subarachnoid spaces, and is reabsorbed via ...